Light Penetration Findings: 

High-power NIR lasers (10-15W) demonstrated significantly greater tissue penetration than low-power LED devices (<1W):

  1. 0.5W LED devices showed no detectable penetration through 2mm of skin

  2. 10W 810/980nm lasers achieved 9-11% penetration through 2mm of skin

  3. 15W 810nm lasers achieved up to 33% penetration through the skin

  4. At 3cm depth into brain tissue, 2.9% of energy from 15W 810nm laser penetrated

  5. Pulsed settings improved penetration compared to continuous wave delivery