Transcranial Photobiomodulation
Chapter 3

4 - Assessment Tools

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IN THIS LESSON

Assessment tools:

  1. Quick Inventory of Depression Symptomatology-Self Report (QIDS)

  2. Beck Depression Inventory (BDI)

  3. Hamilton Depression Rating Scale (HAM-D)

  4. Patient and spousal symptom diaries

  5. SPECT imaging for functional changes

  • Citations:

    1. Henderson TA, Morries LD. Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain? Neuropsychiatr Dis Treat. 2015;11:2191-2208.

    2. Morries LD, Cassano P, Henderson TA. Treatments for traumatic brain injury with emphasis on transcranial near-infrared laser phototherapy. Neuropsychiatr Dis Treat. 2015;11:2159-75.

    3. Henderson TA, Morries LD. Multi-watt near-infrared phototherapy for the treatment of comorbid depression: An open-label single-arm study. Front Psychiatry. 2017;8:187.

    4. Shen Q, Guo H, Yan Y. Photobiomodulation for neurodegenerative diseases: A scoping review. Int J Mol Sci. 2024;25:1625.

    5. Moro C, Valverde A, Dole M, et al. The effect of photobiomodulation on the brain during wakefulness and sleep. Front Neurosci. 2022;16:942536.

    6. Hamblin MR. Shining light on the head: Photobiomodulation for brain disorders. BBA Clin. 2016;6:113-124.

    7. Lapchak PA, Boitano PD, Butte PV, et al. Transcranial near-infrared laser transmission (NILT) profiles: Systematic comparison in four common research species. PLoS ONE. 2015;10:e0127580.

    8. Cassano P, Petrie SR, Hamblin MR, et al. Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis. Neurophotonics. 2016;3:031404.

    9. Tedford CE, DeLapp S, Jacques S, Anders J. Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue. Lasers Surg Med. 2015;47:312-22.

    10. Barrett DW, Gonzalez-Lima F. Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans. Neuroscience. 2013;230:13-23.

    11. Salehpour F, Rasta SH, Mohaddes G, et al. Therapeutic effects of 10-Hz pulsed wave lasers in rat depression model: A comparison between near-infrared and red wavelengths. Lasers Surg Med. 2016;48:695-705.

    12. Naeser MA, Zafonte R, Krengel MH, et al. Significant improvements in cognitive performance post-transcranial, red/near-infrared light-emitting diode treatments in chronic, mild traumatic brain injury: open-protocol study. J Neurotrauma. 2014;31:1008-17.

    13. Xuan W, Agrawal T, Huang L, et al. Low-level laser therapy for traumatic brain injury in mice increases brain-derived neurotrophic factor (BDNF) and synaptogenesis. J Biophotonics. 2015;8:502-11.

    14. Johnstone DM, Moro C, Stone J, et al. Turning on lights to stop neurodegeneration: The potential of near-infrared light therapy in Alzheimer's and Parkinson's disease. Front Neurosci. 2016;9:500.

    15. Wang X, Tian F, Reddy DD, et al. Up-regulation of cerebral cytochrome-c-oxidase and hemodynamics by transcranial infrared laser stimulation: A broadband near-infrared spectroscopy study. J Cereb Blood Flow Metab. 2017;37:3789-3802.